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       bernard        

Daniel Bernard, Ph.D.

Full Professor
Director of the McGill Center for the Study of Reproduction

McGill University

Department of Pharmacology and Therapeutics 

McIntyre building, room 1315

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Phone: 514-398-2525

Fax: 514-398-2045

 

Research Interests 

The Bernard lab investigates molecular mechanisms of pituitary hormone synthesis using in vitro and in vivo approaches.

Research in the lab concerns: 1) signal transduction mechanisms through which members of the transforming growth factor β superfamily regulate pituitary follicle-stimulating hormone (FSH) synthesis, 2) mechanisms of gonadotropin-releasing hormone (GnRH) signaling in pituitary gonadotrope cells, and 3) hypothalamic-pituitary control of thyroid hormone production.

 

Summary of Results:

Most recently, we demonstrated essential roles for SMAD3, SMAD4, and FOXL2 in pituitary specific expression of the FSHbeta subunit gene. We also discovered that loss of function mutations in the Igsf1 gene cause central hypothyroidism via downregulation of pituitary thyrotropin-releasing hormone receptor expression.

 

Lab Members:

 

Name  Position Email Address
Emilie Brûlé MSc Student This email address is being protected from spambots. You need JavaScript enabled to view it.
Christine Kim MSc Student This email address is being protected from spambots. You need JavaScript enabled to view it.
Yining Li PhD Student This email address is being protected from spambots. You need JavaScript enabled to view it.
Luisina.Ongaro Postdoctoral Fellow This email address is being protected from spambots. You need JavaScript enabled to view it.
Gauthier Schang PhD Student This email address is being protected from spambots. You need JavaScript enabled to view it.
Chirine Toufaily Postdoctoral Fellow This email address is being protected from spambots. You need JavaScript enabled to view it.
Ying Wang Research Technician This email address is being protected from spambots. You need JavaScript enabled to view it.
Xiang Zhou Research Technician This email address is being protected from spambots. You need JavaScript enabled to view it. 

 

 

List of Publications:  

http://www.ncbi.nlm.nih.gov/pubmed/?term=bernard+dj%5Bauthor%5D

 

Awards:

Section Director, Frontiers in Reproduction, Marine Biology Laboratory, Woods Hole, MA

Council (Board) of the Endocrine Society

Director, McGill Centre for Research in Reproduction and Development

 

Websites:

www.mcgill.ca/bernardlab

www.mcgill.ca/crrd