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Daniel Dufort, PhD
Professeur associé

McGill University
Dept. of Obstetrics and Gynecology
Research Institute of the McGill University Health Centre
1001, Decarie blvd
Site Glen Block E
CHHD Mail Drop Point EM03211
Montréal (Québec)  H4A 3J1

Email: This email address is being protected from spambots. You need JavaScript enabled to view it. 

Telephone: 514 934-1934 X34743

 

 

Field of research:

The research interests of my lab are in elucidating the embryo-uterine communication that is required for successful for successful implantation. We are using, molecular, embryological and well as genetic approaches to identify the signaling pathways and their roles in the implantation process. Furthermore, we are also interested in elucidating the role of maternal signals in proper development and function of the placenta which are often associated with complications during pregnancy such as Preeclampsia and Preterm Birth.

 

Laboratory members:

Name

Position

Email address

Omar Farah

PhD Student

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Lisa Starr

Postdoctoral Fellow

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Natasha Mokhtarian

MSc Student

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Taghreed Heba

PhD Student

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Shiva Shafiei

PhD Student

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Touhid Opu

MSc Student

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Publications (since 2010):

1. Hari Krishna Thulluru, Craig Park, Daniel Dufort, Gunilla Kleiverda, Cees Oudejans, Marie van Dijk. 2013. Maternal Nodal inversely affects NODAL and STOX1 expression in the fetal placenta. Front Genet. 2013 Aug 27;4:170.

2. Craig B Park and Daniel Dufort. 2013. Nodal Signaling Components during the Preparation, Execution and Maintenance of Embryo Implantation 2013 Jan 24;145(2):R55-64

3. Craig B Park, Francesco J Demayo, John P Lydon, and Daniel Dufort. 2012. Nodal in the Uterus Is Necessary for Proper Placental Development and Maintenance of Pregnancy. Biol Reprod. Jun 28;86(6):194

4. Holowacz T, Huelsken J, Dufort D, van der Kooy D. 2011. Neural stem cells are increased after loss of β-catenin, but neural progenitors undergo cell death. Eur J Neurosci. 2011 Apr;33(8):1366-75

5. Craig Park and Daniel Dufort. Nodal expression in the uterus is regulated by the embryo. Biol Reprod. 2011 Jun;84(6):1103-10. Epub 2011 Jan 26.

6. Craig Park and Daniel Dufort. IFPA Trophoblast Research Award Lecture: The Multifaceted Role of Nodal Signaling During Mammalian Reproduction. Placenta. 2011 Mar;32 Suppl 2:S125-9. Epub 2010 Dec 31.

7. Anna Ferrer-Vaquer, Anna Piliszek, Gianguan Tian, Daniel Dufort and Anna-Katerina Hadjantonakis A sensitive and bright single-cell resolution live imaging reporter of Wnt/ß-catenin signaling in the mouse. BMC Developmental Biology. 2010 Dec 21;10:121. [Epub ahead of print]

8.Abdul-Ghani M, Dufort D, Stiles R, De Repentigny Y, Kothary R, Megeney LA. 2010. Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals. Mol Cell Biol. 2011 Jan;31(1):163-78. Epub 2010 Nov 1.]

9.Amog B, Shalom-Paz E, Dufort D, Tulandi T. (2010) Promoting implantation by local injury to the endometrium. Fertil Steril,. 2010 Nov;94(6):2026-9.

10.Wai T, Ao A, Zhang X, Dufort D, Shoubridge EA. (2010) The role of mitochondrial DNA copy number in mammalian fertility. Biol Reprod. 2010 Jul;83(1):52-62. Epub 2010 Feb 3.