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  chan 

Chan, Peter  M.D., C.M., M.Sc. F.R.C.S.(C)., F.A.C.S.

Director of Male Reproductive Medicine and Professor

McGill University Health Center

Department of Urology

1001 Blvd Decarie, D5-5724

Montreal, Quebec

H4A 3J1

Email: This email address is being protected from spambots. You need JavaScript enabled to view it. 

Phone.: 514 934-1934 ext. 35489

Fax: 514 843-1552

 

Research interests:

  • Genetics in male infertility
  • Chemotherapy impact on male fertility
  • Sperm chromatin structure
  • Assisted reproductive medicine
  • Microsurgery technique development
  • Microsurgery training
  • Multi-media application in medical education

 

Laboratory members: 

 

Name

Position

Email

Phone

Marie-France Lusignan

Research associate

This email address is being protected from spambots. You need JavaScript enabled to view it.">This email address is being protected from spambots. You need JavaScript enabled to view it.

514 934-1934 *76113

Lorraine Lavigne

Research coordinator

This email address is being protected from spambots. You need JavaScript enabled to view it.

514 934-1934 *34037

Xinfang Li

Research assistant

This email address is being protected from spambots. You need JavaScript enabled to view it.

514 934-1934 *76113

 

Lab equipment:

  • CASA
  • MACS
  • KOMET V software

 

List of publications:

Herrero MB, García A, Buckett W, Tulandi T and  Chan P (2016). “ Quebec public funding facilitates fertility preservation to male cancer patients”. Current Oncology 2016 Feb;23(1):20-25.

Feng Y-L, Liao X, Grenier, G, Nguyen N and Chan P (2016). "Determination of 18 Phthalate Metabolites in Human Urine Using Liquid Chromatography-Tandem Mass Spectrometry Equipped with a Core-Shell Column for Rapid Separation" Anal. Methods. [Epub ahead of print].

Manku G, Hueso A, Brimo F, Chan P, Gonzalez-Peramato P, Jabado N, Gayden T, Bourgey M, Riazalhosseini Y, Culty M (2016). Changes in the expression profiles of claudins during gonocyte differentiation and in seminomas. Andrology. 2016 Jan;4(1):95-110

Albert O, Reintsch WE, Chan P, Robaire B (2016). HT-COMET: a novel automated approach for high throughput assessment of human sperm chromatin quality. Hum Reprod. 2016 May;31(5):938-46

Zini A, Grantmyre J and Chan P (2016). Vasectomy: Clinical Guidelines Update. Can Urol Assoc J [www.CUA.org]

Chan D, McGraw S, Klein K, Wallock LM, Konermann C, Plass C, Chan P, Robaire B, Jacob RA, Greenwood CM, Trasler JM. Stability of the human sperm DNA methylome to folic acid fortification and short-term supplementation. Hum Reprod. 2017 Feb;32(2):272-283.

Daumler D, Chan P, Lo KC, Takefman J, Zelkowitz P. Men's knowledge of their own fertility: a population-based survey examining the awareness of factors that are associated with male infertility. Hum Reprod. 2016 Dec;31(12):2781-2790.

Chan, P.T. (2011). Management options of varicoceles. Ind. J. Urol. 27(1):65-73.

Zohni K, Zhang X, Tan SL, Chan P, Nagano MC (2012). The efficiency of male fertility restoration is dependent on the recovery kinetics of spermatogonial stem cells after cytotoxic treatment with busulfan in mice. Hum Reprod. 27(1):44-53.

O’Flaherty C, Chan PT, Hales BF, Robaire B. (2012). Sperm chromatin structure components are differentially repaired in cancer survivors. J Androl. 33(4): 629-636.

Maselli J, Hales BF, Chan P, Robaire B. (2012). Exposure to belomycin, etoposide, and cis-platinum alters rat sperm chromatin integrity and sperm head protein profile. Biol. Reprod. 31; 86(5):166, 1-10.

Chan PT (2013). The evolution and refinement of vasoepididymostomy techniques. Asian J Androl. 2013 Jan;15(1):49-55.

Gong S, San Gabriel MC, Zini A, Chan P, O'Flaherty C. (2012) Low amounts and high thiol oxidation of peroxiredoxins in spermatozoa from infertile men. J Androl. 33(6):1342-51.

Zohni K, Zhang X, Tan SL, Chan P, Nagano M. (2012) CD9 is expressed on human male germ cells that have a long-term repopulation potential after transplantation into mouse testes. Biol Reprod. 2;87(2):27.

Dubé É, Dufresne J, Chan PTK and Cyr DG. (2012).  Epidermal growth Factor regulates connexion 43 in the human epididymis: role of gap junctions in azoospermia. Human Reprod 27, 2285-2296

Delbes G, Herrero, MB, Troeung, E-T, Chan, PTK. (2013) The use of complimentary assays to evaluate the enrichment of human sperm quality in asthenoteratozoospermic and teratozoospermic samples processed with Annexin-V magnetic activated cell. Andrology. 1(5):698-706.

Kichine E, Di Falco M, Hales BF, Robaire B, Chan P. (2013). Analysis of the sperm head protein profiles in fertile men: Consistency across time in the levels of expression of heat shock proteins and peroxiredoxins. PLoS-One8(10): e77471.

Herrero MB, Delbes G, Chung JT, Son, WY, Holzer H, Buckett W and Chan P. (2013). The use of annexin V coupled with magnetic activated cell sorting in crypreserved spermatozoa from a male cancer survivor: Healthy twin newborns after two previous ICSI failures. J. Assisted Reproduction and Genetics. 30(11):1415-9.

Son WY, Chung JT, Henderson S, Reinblatt S, Buckett W, Chan PT, Holzer H. (2013)

Fertilization and embryo development with spermatozoa obtained from testicular sperm extraction into oocytes generated from human chorionic gonadotropin-primed in vitro maturation cycles. Fertil. Steril. 100(4):989-993.

Zelkowitz P, King L, Whitley R, Tulandi T, Ells C, Feeley N, Gold I, Rosberger Z, Chan P et al (2015). A Comparison of Immigrant and Canadian-Born Patients Seeking Fertility Treatment. J Immigr Minor Health. 17(4):1033-40.

Garcia A, Herrero MB, Holzer H, Tulandi T, Chan P. (2015) Assisted reproductive outcomes of male cancer survivors. J Cancer Surviv. 9(2): 208-214.

Jarvi K, Lo K, Grober E, Mak V, Fischer A, Grantmyre J, Zini A, Chan P, Patry G, Chow V, Domes T. The workup and management of azoospermic males. Can Urol Assoc J. 2015 Jul-Aug;9(7-8):229-35.

Esteves S and Chan P (2015). "A Systematic Review of Recent Clinical Practice Guidelines and Best Practice Statements for the Evaluation of the Infertile Male". Int Urol Nephrol. 2015 Sep;47(9):1441-56


Awards

2017 First Prize on Fundamental Research, St Lawrence Urological Group Annual Meeting

2013 Annual Outstanding Contribution Award, Prostate Cancer Network Canada

2003, 2008, 2010, 2015 Everett C. Reid Award for Excellence in the Teaching of Urology, Department of Urology, McGill University Health Center