- 514 934-1934 Ext. 76184
- Research Institute of the McGill University Health Centre,
1001 boul. Décarie,
Montréal, QC, H4A 3J1
Highly regulated degradation of proteins plays important roles in the proliferative, meiotic and cellular remodeling phases of spermatogenesis. We previously demonstrated the activation of ubiquitination during spermatogenesis and are now identifying key ubiquitin system enzymes involved in this process. Our recent studies have focused on the roles of the Huwe1 ubiquitin ligase and the USP2 and USP19 deubiquitinating enzymes.